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Dhillon, S
These molecules recruit the speck-like protein, resulting in caspase-1 activation, subsequent GSDMD cleavage, and interleukins interleukin (IL)-18 and IL-1 maturation (159, 163)
Mol Cell Endocrinol 546:111572
This unique mechanism has delivered some of the most dramatic results ever seen in obesity treatment, with participants in Phase 2 trials losing up to 24% of their body weight in under a year
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